294 



THE MICROSCOPIST. 



cells in epithelioma. It may be said of this structure, as 

 well perhaps of all varieties of carcinoma, that it is com- 

 posed of epithelium run mad, epithelium become heterol- 

 ogous, extending beyond its normal limits into subjacent 

 tissues. Epithelioma is first seen as a small foul ulcer 

 with indurated edges, or as an induration or nodule which 



Section of a cylinder of epithelial cells, under a magnifying power of 500. a. The 

 cylinder itself, with the characteristic stratification of its cells, a younger and an older 

 pearly globule. 6. The stroma, very rich in cells at c, and contributing directly to the 

 enlargement by apposition of the cylinder. After RINDFLEISCH. 



subsequent^ ulcerates. The surface of the ulcer is often 

 villous, and the cut surface yields on pressure a small 

 quantity of turbid fluid, or a thick curdy material like 

 the sebaceous matter of the glands of the skin. This is 

 composed of epithelium. Epithelioma often occurs on 

 the lower lip at the junction of skin and mucous mem- 

 brane. It may also grow on the tongue, scrotum, etc., 

 and by its development may involve any tissue whatever. 

 Wagner describes three varieties of epithelioma : the 

 papillary, or warty pavement-cell cancer, whose surface 



