VACCINATION AGAINST SMALLPOX 157 



disease, but no indisposition ensued. During the time she 

 remained in the infected room, variolous matter was inserted 

 into both her arms, but without any further effect than in 

 the preceding case. 



CASE III. John Phillips, a tradesman of this town, had 

 the cow-pox at so early a period as nine years of age. At 

 the age of sixty-two I inoculated him, and was very careful 

 in selecting matter in its most active state. It was taken 

 from the arm of a boy just before the commencement of the 

 eruptive fever, and instantly inserted. It very speedily pro- 

 duced a sting-like feel in the part. An efflorescence appear- 

 ed, which on the fourth day was rather extensive, and some 

 degree of pain and stiffness were felt about the shoulder; but 

 on the fifth day these symptoms began to disappear, and in 

 a day or two after went entirely off, without producing any 

 effect on the system. 



CASE IV. Mary Barge, of Woodford, in this parish, was 

 inoculated with variolous matter in the year 1791. An 

 efflorescence of a palish red colour soon appeared about the 

 parts where the matter was inserted, and spread itself rather 

 extensively, but died away in a few days without producing 

 any variolous symptoms." She has since been repeatedly 

 employed as a nurse to smallpox patients, without expe- 

 riencing any ill consequences. This woman had the cow- 

 pox when she lived in the service of a farmer in this parish 

 thirty-one years before. 



CASE V. Mrs. H , a respectable gentlewoman of this 



town, had the cow-pox when very young. She received the 

 infection in rather an uncommon manner: it was given by 

 means of her handling some of the same utensils 7 which 



* It is remarkable that variolous matter, when the system is disposed to 

 reject it, should excite inflammation on the part to which it is applied more 

 speedily than when it produces the smallpox. Indeed, it becomes almost 

 criterion by which we can determine whether the infection will be received 

 or not. It seems as if a change, which endures through life, had been pro- 

 duced in the action, or disposition to action, in the vessels of the skin; and 

 it is remarkable, too, that whether this change has been effected by the 

 smallpox or the cow-pox that the disposition to sudden cuticular inflamma- 

 tion it the same on the application ot variolous matter. 



T When the cow-pox has prevailed in the dairy, it has often been communi- 

 cated to those who have not milked the cows, by the handle of the milk pail* 



