158 EDWARD JENNER 



were in use among the servants of the family, who had the 

 disease from milking infected cows. Her hands had many 

 of the cow-pox sores upon them, and they were communi- 

 cated to her nose, which became inflamed and very much 



swollen. Soon after this event Mrs. H was exposed to 



the contagion of the smallpox, where it was scarcely pos- 

 sible for her to have escaped, had she been susceptible of it, 

 as she regularly attended a relative who had the disease in 

 so violent a degree that it proved fatal to him. 



In the year 1778 the smallpox prevailed very much at 



Berkeley, and Mrs. H , not feeling perfectly satisfied 



respecting her safety (no indisposition having followed her 

 exposure to the smallpox), I inoculated her with active 

 variolous matter. The same appearance followed as in the 

 preceding cases an efflorescence on the arm without any 

 effect on the constitution. 



CASE VI. It is a fact so well known among our dairy 

 farmers that those who have had the smallpox either escape 

 the cow-pox or are disposed to have it slightly, that as soon 

 as the complaint shews itself among the cattle, assistants are 

 procured, if possible, who are thus rendered less susceptible 

 of it, otherwise the business of the farm could scarcely go 

 forward. 



In the month of May, 1796, the cow-pox broke out at Mr. 

 Baker's, a farmer who lives near this place. The disease 

 was communicated by means of a cow which was purchased 

 in an infected state at a neighbouring fair, and not one of 

 the farmer's cows (consisting of thirty) which were at that 

 time milked escaped the contagion. The family consisted of 

 a man servant, two dairymaids, and a servant boy, who, with 

 the farmer himself, were twice a day employed in milking 

 the cattle. The whole of this family, except Sarah Wynne, 

 one of the dairymaids, had gone through the smallpox. The 

 consequence was that the farmer and the servant boy escaped 

 the infection of the cow-pox entirely, and the servant man 

 and one of the maid servants had each of them nothing 

 more then a sore on one of their fingers, which produced 

 no disorder in the system. But the other dairymaid, Sarah 

 Wynne, who never had the smallpox, did not escape in 





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