VACCINATION AGAINST SMALLPOX 159 



easy a manner. She caught the complaint from the cows, 

 and was affected with the symptoms described on page 

 154 in so violent a degree that she was confined to her bed, 

 and rendered incapable for several days of pursuing her 

 ordinary vocations in the farm. 



March 28, 1797, I inoculated this girl and carefully rubbed 

 the variolous matter into two slight incisions made upon the 

 left arm. A little inflammation appeared in the usual man- 

 ner around the parts where the matter was inserted, but so 

 early as the fifth day it vanished entirely without producing 

 any effect on the system, 



CASE VII. Although the preceding history pretty clearly 

 evinces that the constitution is far less susceptible of the 

 contagion of the cow-pox after it has felt that of the small- 

 pox, and although in general, as I have observed, they who 

 have had the smallpox, and are employed in milking cows 

 which are infected with the cow-pox, either escape the dis- 

 order, or have sores on the hands without feeling any gen- 

 eral indisposition, yet the animal economy is subject to some 

 variation in this respect, which the following relation will 

 point out: 



In the summer of the year 1796 the cow-pox appeared at 

 the farm of Mr. Andrews, a considerable dairy adjoining to 

 the town of Berkeley. It was communicated, as in the pre- 

 ceding instance, by an infected cow purchased at a fair in 

 the neighbourhood. The family consisted of the farmer, his 

 wife, two sons, a man and a maid servant; all of whom, 

 except the farmer (who was fearful of the consequences), 

 bore a part in milking the cows. The whole of them, exclu- 

 sive of the man servant, had regularly gone through the 

 smallpox; but in this case no one who milked the cows 

 escaped the contagion. All of them had sores upon their 

 hands, and some degree of general indisposition, preceded 

 by pains and tumours in the axillae: but there was no com- 

 parison in the severity of the disease as it was felt by the 

 servant man, who had escaped the smallpox, and by those of 

 the family who had not, for, while he was confined to his 

 bed, they were able, without much inconvenience, to follow 

 their ordinary business. 



