VACCINATION AGAINST SMALLPOX 161 



year 1780. One of the horses belonging to the farm had 

 sore heels, and it fell to his lot to attend him. By these 

 means the infection was carried to the cows, and from the 

 cows it was communicated to. Smith. On one of his hands 

 were several ulcerated sores, and he was affected with such 

 symptoms as have been before described. 



In the year 1791 the cow-pox broke out at another farm 

 where he then lived as a servant, and he became affected with 

 it a second time ; and in the year 1794 he was so unfortunate 

 as to catch it again. The disease was equally as severe the 

 second and third time as it was on the first. 8 



In the spring of the year 1795 he was twice inoculated, 

 but no affection of the system could be produced from the 

 variolous matter ; and he has since associated with those who 

 had the smallpox in its most contagious state without feeling 

 any effect from it. 



CASE X. Simon Nichols lived as a servant with Mr. 

 Bromedge, a gentleman who resides on his own farm in this 

 parish, in the year 1782. He was employed in applying 

 dressings to the sore heels of one of his master's horses, 

 and at the same time assisted in milking the cows. The cows 

 became affected in consequence, but the disease did not shew 

 itself on their nipples till several weeks after he had begun 

 to dress the horse. He quitted Mr. Bromedge's service, and 

 went to another farm without any sores upon him; but here 

 his hands soon began to be affected in the common way, and 

 he was much indisposed with the usual symptoms. Con- 

 cealing the nature of the malady from Mr. Cole, his new 

 master, and being there also employed in milking, the cow- 

 pox was communicated to the cows. 



Some years afterward Nichols was employed in a farm 

 where the smallpox broke out, when I inoculated him with 

 several other patients, with whom he continued during the 

 whole time of their confinement. His arm inflamed, but 

 neither the inflammation nor his associating with the in- 

 oculated family produced the least effect upon his con- 

 stitution. 



This is not the case in general second attack it commonly very slight 

 and so, I am informed, it it among the cows. 



(6) UC XXXVHI 



