

164 EDWARD JENNER 



for, on being exposed to the infection upwards of twenty 

 years afterwards, he caught the disease, which took its 

 regular course in a very mild way. There certainly was a 

 difference perceptible, although it is not easy to describe it, 

 in the general appearance of the pustules from that which 

 we commonly see. Other practitioners who visited the 

 patient at my request agreed with me in this point, though 

 there was no room left for suspicion as to the reality of the 

 disease, as I inoculated some of his family from the pustules, 

 who had the smallpox, with its usual appearances, in conse- 

 quence. 



CASE XVI. Sarah Nelmes, a dairymaid at a farmer's 

 near this place, was infected with the cow-pox from her 

 master's cows in May, 1796. She received the infection on 

 a part of her hand which had been previously in a slight 

 degree injured by a scratch from a thorn. A large pustulous 

 sore and the usual symptoms accompanying the disease were 

 produced in consequence. The pustule was so expressive of 

 the true character of the cow-pox, as it commonly appears 

 upon the hand, that I have given a representation of it in 

 the annexed plate. The two small pustules on the wrists 

 arose also from the application of the virus to some minute 

 abrasions of the cuticle, but the livid tint, if they ever had 

 any, was not conspicuous at the time I saw the patient. The 

 pustule on the forefinger shews the disease in an earlier 

 stage. It did not actually appear on the hand of this young 

 woman, but was taken from that of another, and is annexed 

 for the purpose of representing the malady after it has newly 

 appeared. 



CASE XVII. The more accurately to observe the progress 

 of the infection I selected a healthy boy, about eight years 

 old, for the purpose of inoculation for the cow-pox. The 

 matter was taken from a sore on the hand of a dairymaid, 10 

 who was infected by her master's cows, and it was inserted, 

 on the I4th of May, 1796, into the arm of the boy by means 

 of two superficial incisions, barely penetrating the cutis, each 

 about half an inch long. 



"From the sore on the hand of Sarah Nelmes. See the preceding 



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