166 EDWARD JENNEB 



William Wherret, and William Haynes, who in consequence 

 became affected with sores in their hands, followed by in- 

 flamed lymphatic glands in the arms and axillae, shivering* 

 succeeded by heat, lassitude, and general pains in the limbs. 

 A single paroxysm terminated the disease; for within 

 twenty-four hours they were free from general indisposi- 

 tion, nothing remaining but the sores on their hands. Haynes 

 and Virgoe, who had gene through the smallpox from inocu- 

 lation, described their feelings as very similar to those which 

 affected them on sickening with that malady. Wherret never 

 had had the smallpox. Haynes was daily employed as one 

 of the milkers at the farm, and the disease began to shew 

 itself among the cows about ten days after he first assisted 

 in washing the mare's heels. Their nipples became sore in 

 the usual way, with bluish pustules; but as remedies were 

 early applied, they did not ulcerate to any extent. 



CASE XVIII. John Baker, a child of five years old, was 

 inoculated March 16, 1798, with matter taken from a pustule 

 on the hand of Thomas Virgoe, one of the servants who had 

 been infected from the mare's heels. He became ill on the 

 sixth day with symptoms similar to those excited by cow- 

 pox matter. On the eighth day he was free from indispo- 

 sition. 



There was some variation in the appearance of the pustule 

 on the arm. Although it somewhat resembled a smallpox 

 pustule, yet its similitude was not so conspicuous as when 

 excited by matter from the nipple of the cow, or when the 

 matter has passed from thence through the medium of the 

 human subject. 



This experiment was made to ascertain the progress and 

 subsequent effects of the disease when thus propagated. We 

 have seen that the virus from the horse, when it proves in- 

 fectious to the human subject, is not to be relied upon as 

 rendering the system secure from variolous infection, but 

 that the matter produced by it upon the nipple of the cow is 

 perfectly so. Whether its passing from the horse through 

 the human constitution, as in the present instance, will pro- 

 duce a similar effect, remains to be decided This would 

 now have been effected, but the boy was rendered unfit 





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