VACCINATION AGAINST SMALLPOX 167 



inoculation from having felt the effects of a contagious fever 

 in a workhouse soon after this experiment was made. 



CASE XIX. William Summers, a child of five years and 

 a half old, was inoculated the same day with Baker, with 

 matter taken from the nipples of one of the infected cows, 

 at the farm alluded to. He became indisposed on the sixth 

 day, vomited once, and felt the usual slight symptoms till 

 the eighth day, when he appeared perfectly well. The prog- 

 ress of the pustule, formed by the infection of the virus, was 

 similar to that noticed in Case XVII, with this exception, 

 its being free from the livid tint observed in that instance. 



CASE XX. From William Summers the disease was trans- 

 ferred to William Pead, a boy of eight years old, who was 

 inoculated March 28th. On the sixth day he complained of 

 pain in the axilla, and on the seventh was affected with the 

 common symptoms of a patient sickening with the smallpox 

 from inoculation, which did not terminate till the third day 

 after the seizure. So perfect was the similarity to the vari- 

 olous fever that I was induced to examine the skin, con- 

 ceiving there might have been some eruptions, but none 

 appeared. The efflorescent blush around the part punctured 

 in the boy's arm was so truly characteristic of that which 

 appears on variolous inoculation that I have given a repre- 

 sentation of it The drawing was made when the pustule 

 was beginning to die away and the areola retiring from the 

 centre. 



CASE XXI. April 5th: Several children and adults were 

 inoculated from the arm of William Pead. The greater part 

 of them sickened on the sixth day, and were well on the 

 seventh, but in three of the number a secondary indisposition 

 arose in consequence of an extensive erysipelatous inflamma- 

 tion which appeared on the inoculated arms. It seemed to 

 arise from the state of the pustule, which spread out, accom- 

 panied with some degree of pain, to about half the diameter 

 of a sixpence. One of these patients was an infant of half 

 a year old. By the application of mercurial ointment to the 

 inflamed parts (a treatment recommended under similar cir- 



