208 EDWARD JENNER 



the smallpox, the system not being in the least deranged, OS 

 the arms inflamed, although they were repeatedly inoculated, 

 and associated with others who were labouring under the 

 disease; one of them was the son of a farrier." 



Mr. Tierny, Assistant Surgeon of the South Gloucester 

 Regiment of Militia, has obliged me with the following in- 

 formation : 



" That in the summer of the year of 1798 he inoculated a 

 great number of the men belonging to the regiment, and that 

 among them he found eleven who, from having lived in 

 dairies, had gone through the cow-pox. That all of them 

 resisted the smallpox except one, but that on making the most 

 rigid and scrupulous enquiry at the farm in Gloucestershire, 

 where the man said he lived when he had the disease, and 

 among those with whom, at the same time, he declared he 

 had associated, and particularly of a person in the parish, 

 whom he said had dressed his fingers, it most clearly appeared 

 that he aimed at an imposition, and that he never had been 

 affected with the cow-pox." 1! Mr. Tierny remarks that the 

 arms of many who were inoculated a^fter having had the 

 cow-pox inflamed very quickly, and that in several a little 

 ichorous fluid was formed. 



Mr. Cline, who in July last was so obliging at my request 

 as to try the effieacy of the cow-pox virus, was kind enough 

 to give me a letter on the result of it, from which the follow- 

 ing is an extract: 



"Mr DEAR SIR: 



" The cow-pox experiment has succeeded admirably. The 

 child sickened on the seventh day, and the fever, which was 

 moderate, subsided on the eleventh. The inflammation aris- 

 ing from the insertion of the virus extended to about four 

 inches in diameter, and then gradually subsided, without hav- 

 ing been attended with pain or other inconvenience. There 

 were no eruptions. 



"I have since inoculated him with smallpox matter in three 

 places, which were slightly inflamed on the third day, and 

 then subsided. 



13 The public cannot be too much upon their guard respecting persons of 

 this description. 





