210 EDWARD JENNER 



vivid red colour. The pulse natural; tongue of its natural 

 hue; no loss of appetite or any symptom of indisposition. 



9th: The inoculated pustule on the arm this evening 

 began to inflame, and gave the child uneasiness; he cried 

 and pointed to the seat of it, and was immediately after- 

 wards affected with febrile symptoms. At the expiration 

 of two hours after the seizure a plaster of ung. hydrarg. 

 fort, was applied, and its effect was very quickly per- 

 ceptible, for in ten minutes he resumed his usual looks 

 and playfulness. On examining the arm about three hours 

 after the application of the plaster its effects in subduing 

 the inflammation were very manifest. 



loth: The spots on the arms have disappeared, but there 

 are three visible in the face. 



nth: Two spots on the face are gone; the other barely 

 perceptible. 



I3th: The pustule delineated in the second plate in the 

 Treatise on the Variolae Vaccinae is a correct representa- 

 tion of that on the child's arm as it appears at this time. 



1 4th: Two fresh spots appear on the face. The pustule 

 on the arm nearly converted into a scab. As long as any 

 fluid remained in it it was limpid. 



James Hill, four years old, was inoculated on the same 

 day, and with part of the same matter which infected 

 Stephen Jenner. It did not appear to have taken effect 

 till the fifth day. 



7th: A perceptible vesicle: this evening the patient became 

 a little chilly ; no pain or tumour discoverable in the axilla. 



8th: Perfectly well. 



9th : The same. 



loth: The vesicle more elevated than I have been ac- 

 customed to see it, and assuming more perfectly the vario- 

 lous character than is common with the cow-pox at this 

 stage. 



nth: Surrounded by an inflammatory redness, about the 

 size of a shilling, studded over with minute vesicles. The 

 pustule contained a limpid fluid till the fourteenth day, after 

 which it was incrusted over in the usual manner; but this in- 

 crustation or scab being accidentally rubbed off, it was 

 slow in healing. 



