224 EDWARD JENNER 



Although the susceptibility of the virus of the cow- 

 pox is, for the most part, lost in those who have had the 

 smallpox, yet in some constitutions it is only partially 

 destroyed, and in others it does not appear to be in the 

 least diminished. 



By far the greater number on whom trials were made 

 resisted it entirely; yet I found some on whose arm the 

 pustule from inoculation was formed completely, but with- 

 out producing the common efflorescent blush around it, or 

 any constitutional illness, while others have had the disease 

 in the most perfect manner. A case of the latter kind 

 having been presented to me by Mr. Fewster, Surgeon, of 

 Thornbury, I shall insert it: 





" Three children were inoculated with the vaccine mat- 

 ter you obligingly sent me. On calling to look at their 

 arms three days after I was told that John Hodges, one 

 of the three, had been inoculated with the smallpox when 

 a year old, and that he had a full burthen, of which his 

 face produced plentiful marks, a circumstance I was not 

 before made acquainted with. On the sixth day the arm 

 of the boy appeared as if inoculated with variolous mat- 

 ter, but the pustule was rather more elevated. On the 

 ninth day he complained of violent pain in his head and 

 back, accompanied with vomiting and much fever. The 

 next day he was very well and went to work as usual. 

 The punctured part began to spread, and there was the 

 areola around the inoculated part to a considerable extent. 



" As this is contrary to an assertion made in the Medical 

 and Physical Journal, No. 8, I thought it right to give 

 you this information, and remain, 



" Dear sir, etc., 



"J. FEWSTER." 



It appears, then, that the animal economy with regard to 

 the action of this virus is under the same laws as it is with 

 respect to the variolous virus, after previously feeling its 

 influence, as far as comparisons can be made between the 

 two diseases. 



Some striking instances of the power of the cow-pox ii 



