VACCINATION AGAINST SMALLPOX 227 



appearance around it, and that as it approached the centra it 

 was nearly in an erysipelatous state. But the most remark- 

 able part of this history is that, on the fourth day afterwards, 

 so soon as the efflorescence began to die away upon the arm 

 and the pustule to dry up, the scarlatina again appeared, her 

 throat became sore, the rash spread all over her. She went 

 fairly through the disease with its common symptoms. 



That these were actually cases of scarlatina was rendered 

 certain by two servants in the family falling ill at the same 

 time with the distemper, who had been exposed to the infec- 

 tion with the young ladies. 



Some there are who suppose the security from the small- 

 pox obtained through the cow-pox will be of a temporary 

 nature only. This supposition is refuted not only by analogy 

 with respect to the habits of diseases of a similar nature, 

 but by incontrovertible facts, which appear in great numbers 

 against it To those already adduced in the former part of 

 my first treatise 7 many more might be adduced were it deemed 

 necessary ; but among the cases I refer to, one will be found 

 of a person who had the cow-pox fifty-three years before the 

 effect of the smallpox was tried upon him. As he completely 

 resisted it, the intervening period I conceive must necessarily 

 satisfy any reasonable mind. Should further evidence be 

 thought necessary, I shall observe that, among the cases pre- 

 sented to me by Mr. Fry, Mr. Darke, Mr. Tierny, Mr. H. 

 Jenner, and others, there were many whom they inoculated 

 ineffectually with variolous matter, who had gone through 

 the cow-pox many years before this trial was made. 



It has been imagined that the cow-pox is capable of being 

 communicated from one person to another by effluvia without 

 the intervention of inoculation. My experiments, made with 

 the design of ascertaining this important point all tend to 

 establish my original position, that it is not infectious except 

 by contact I have never hesitated to suffer those on whose 

 arms there were pustules exhaling the effluvia from associat- 

 ing or even sleeping with others who never had experienced 

 either the cow-pox or the smallpox. And, further, I have 

 repeatedly, among children, caused the uninfected to breathe 

 1 Set pages aiy. art. at* MI, aaj. etc. 



