138 Botanic Drugs 



tration, 4 grains in 1.6 to 3.2 ounces physiologic salt 

 solution, with 5 or 10 drops epinephrine solution 

 (1:1,000). For instillations and injections, solu- 

 tions of 1^2 grains in 150 or 75 grains salt solution 

 (by weight), with or without 10 drops epinephrine 

 solution (1:1,000). In ophthalmology, 1 to 10%; 

 rhinolaryngology, 5 to 20%. Internal dose for 

 adults, 3 to 7}/<z grains. 



ORTHOFORM NEW is practically non-toxic and 

 but slightly soluble, not penetrating the tissues. 

 Used internally to relieve the pain of gastric ulcer 

 (8 to 15 grains) and as an analgesic to wounds, in 

 dentistry, hay fever, etc. 



PROPAESIN is practically non-toxic, said to be 

 stronger than anesthesin. It is slightly astringent 

 and is used similarly to other agents of its class. 

 Dose: 4 to 8 grains. 



STOVAINE is one-half as toxic as cocaine and is 

 similar to alypin. The internal dose is 1-30 grain 

 in pill form. In the eye, up to 4%; and in laryn- 

 gology, up to 10%. May be sterilized at 115 C. 



TROPACOCAINE HYDROCHLORIDE is one-half as 

 toxic as cocaine; it produces little dilatation of the 

 pupil. Used in 3 to 10% aqueous solutions contain- 

 ing 0.6% sodium chloride. Put up in 1 -grain ster- 

 ilized tubes. 



The cocaine substitutes are displacing cocaine 

 in several lines of usage. The fact that some of them 

 may be sterilized by boiling and without losing 

 activity makes them of great importance to the 

 surgeon. 



Also see quinine and urea hydrochloride under 

 "Quinine." 



