146 Botanic Drugs 



COTARNINE 



By oxidation, conversion otnarcotine into an arti- 

 ficial alkaloid is possible; this is called cotarnine. 

 It is used to restrain uterine hemorrhage due to 

 endometritis, menorrhagia, and congestive troubles. 

 It is not effective in post-partum hemorrhage. 

 Locally the drug is a useful application in epistaxis 

 and other forms of hemorrhage from small vessels. 

 There are two forms on the market; the first, STYP- 

 TICIN, is cotarnine hydrochloride. Dose: % to 

 1^ grains in pill or capsule; hypodermically 2 cc. 

 of a 10% solution. STYPTOL is cotarnine phthalate. 

 Dose: tablets of % grain each, 3 to 9 tablets a day, 

 the latter in severe cases of dysmenorrhea; subcu- 

 taneously, in severe hemorrhage., 3 grains in 30 minims 

 of water. Locally as a dusting powder. (Note. 

 Narcotine is not narcotic, but Harrison Act applies.) 



CRATAEGU8 



HAWTHORNE BERRIES, Crataegus oxyacantha. Ho- 

 meopathic books of some years ago classed .crataegus 

 as a drug akin to strophanthus when used in doses 

 of 1 to 15 drops of the tincture; and it was recom- 

 mended in chronic cardiac lesions and general ana- 

 sarca, rather large doses being given in dyspnea. 

 Later, the drug was recommended by Eclectic 

 authorities in angina pectoris and precordial oppres- 

 sion. Some very fantastic literature has appeared 

 relative to this drug. An examination of this lit- 

 erature has brought to light nothing sufficiently 

 critical to be of much value. 



Yet, notwithstanding the fact that there is no 



