192 Botanic Drugs 



especially the colorless ones, are used externally and 

 sometimes internally as well. 



HYDRASTINE is used much as is hydrastis and also 

 in uterine hemorrhage, and its hydrochloride the 

 same. But the hydrochloride salt is preferable for 

 local use, as in conjunctivitis (0.1 to 0.5% solutions), 

 gonorrhea (0.25 to 0.5%), skin diseases (1%). 



HYDRASTININE HYDROCHLORIDE is the better uter- 

 ine hemostatic. Doses are given under its descrip- 

 tion. Subcutaneously use 8 to 15 minims of a 10% 

 aqueous solution. See also "Cotarnine," "Styp- 

 ticin," and "Styptol." These products, but not the 

 hydrastis alkaloids, come under the provisions of 

 the Harrison Act. 



HYOSCYAMUS 



HENBANE, Hyoscyamus niger. The leaves are 

 universally official; the seed in Denmark, France, 

 Mexico, and Spain. 



PHARMACOLOGY. First read what was said under 

 "Belladonna" and note that atropine and hyoscy- 

 amine are pharmacologically alike, and that hyoscine 

 and scopolamine are also similar. So, then, pharma- 

 cologically, atropine and hyoscine are the two dis- 

 similar alkaloids. The discussion of atropine, q. v., 

 practically covers the subject, and it only remains 

 to say that hyoscine (scopolamine) is an alkaloid 

 of the atropine group in which the narcotic effect 

 predominates. Hyoscyamus has a shorter stimu- 

 lant action than has belladonna, and it is more nar- 

 cotic, though it acts more like belladonna than like 

 opium. 



Whole-plant products are standardized according 

 to the percentage of the combined mydriatic alka- 



