256 Botanic Drugs 



injured by its unwise advocacy in diphtheria, 

 tetanus, primary syphilis, and other infections. 

 Needless to say, it has no place whatever in such 

 serious pathology. 



Give a good fl. made from the recent root in doses 

 of 1 to 3 minims. I don't believe preparations of the 

 berries to be worth employing. Homeopathic phar- 

 macies supply a good 25% cerate. Phytolacca 

 should almost invariably be combined with pur- 

 gative and diuretic eliminants, as by itself it is less 

 effective. 



PILOCARPUS 



JABORANDI, Pilocarpus species, official in U. S. P. 

 IX and eight other standards; P. Jaborandi, PER- 

 NAMBUCO JABORANDI, in five countries, including 

 the U. S.; P. microphyllus, MARANHAM JABORANDI, 

 only in the U. S. (a very valuable species); P. pen- 

 natifolius, Rio JABORANDI, in four countries but not 

 in the U. S. 



PILOCARPINE is the active alkaloid in all. There 

 are also small quantities of isopilocarpine, pilocarpi- 

 dine, and pilosine. "Jaborine" has been stated to 

 be an antagonistic alkaloid with an atropine-like 

 action, and which occurs more in P. Jaborandi than 

 in P. microphyllus; but the existence of this alkaloid 

 is now denied. The hydrochloride and the nitrate 

 of pilocarpine are official (in an average dose of 1-6 

 grain by mouth and 1-12 grain hypodermatically) ; 

 but the nitrate is the best salt, the hydrochloride 

 being deliquescent. 



PHARMACOLOGY OF PILOCARPINE. Stimulates cer- 

 ebral and sacral autonomic nerves and glandular 

 secretion from the salivary glands, the glands of 

 the buccal mucous membrane, trachea and stomach, 



