Botanic Remedies 291 



tolerate small quantities of levulose, and these 

 synthetic products be unnecessary. 



SAFROLUM 



SAFROL occurs in the oils of sassafras, camphor, 

 star-anise, cinnamon leaves, and in various barks. 

 It constitutes 80% of the OIL OF SASSAFRAS. 



SASSAFRAS, Sassafras officinale, or S. variifolium, 

 is official in the form of the bark and the oil in the 

 U. S. and a few other countries. The pith was official 

 in the U. S. P. VIII, but in no other standard. The 

 root is official in Japan, and the wood in Austria, 

 Germany, the Netherlands, and Spain. 



Sassafras is an aromatic stimulant. The oil is 

 used as a flavoring agent. Mucilage of sassafras 

 pith is a good vehicle and is a demulcent used in 

 acute febrile and inflammatory affections. Externally 

 the oil is a mild rubefacient, and it may be given 

 internally in doses of 3 minims. The dose of safrol 

 is 5 minims. 



SYNTHETIC OIL OF SASSAFRAS, the SAFROL of the 

 U. S. P., is the methylene ether of allyl pyrocatechol, 

 and it serves every purpose for which oil of sassafras 

 is employed externally. It may be given internally 

 in 5-minim doses, though the natural oil in 3-minim 

 doses is preferable. 



SALIX 



WHITE WILLOW, Salix Alba. Not official, but is 

 a source of salicin. The willow is tonic, antiperiodic, 

 and an astringent bitter. Used in decoction of the 

 bark. 



BLACK WILLOW, Salix nigra. The bark of the 

 root has been used as is white willow. This plant 



