BACILLI OF PSEUDO-INFLUENZA 179 



to elucidate the cause of the nervous phenomena frequently observed in 

 cases of influenza in man. 



Immunity. In Pfeiffer's experiments monkeys did not react so 

 strongly to a second injection of influenza bacilli as they did to the 

 first ; this fact he considered an indication of immunity. Man can 

 with certainty be attacked several times with influenza, sometimes 

 the same individual during the course of one epidemic. It follows, 

 then, that in man there is no immunity resulting from an attack of 

 influenza ; any such condition can only be considered as temporary and 

 only lasting a very short time. 



BACILLI OF PSEUDO-INFLUENZA. 



In a broncho -pneumonic centre in a diphtheritic child PfeifFer found 

 a bacillus which in appearance and staining reaction resembled the 

 influenza bacillus, and also grew in a similar manner on blood agar. 

 Similar bacilli have also been isolated by other investigators in otitis 

 media and influenza. PfeifFer considers they are allied to the influenza 

 bacillus, and designates them pseudo-influenza bacilli. They are dis- 

 tinguished from the genuine influenza bacilli by their growth on culture 

 media, being much more pronounced in all dimensions in twenty-four 

 hours, and by their tendency to form long false filaments, a condition 

 rarely occurring in cultures of the genuine bacilli. 



The Septicaemia Hsemorrhagica Group of Bacteria. 

 BACILLUS BOVISEPTICUS. 



(Ger. Bac der Wild und Rinder-seuche.) 



This disease occurs in two forms : one form is characterised by 

 oedema of the skin and subcutaneous tissue particularly of the head 

 and swelling of the tongue ; the second or pectoral form is character- 

 ised by pleuro-pneumonia, swelling of the interstitial tissue of the lungs, 

 pleuritis and pericarditis. Both forms generally run into haemorrhagic 

 enteritis. 



The mortality is about 90 per cent. 



The Wild and Rinder-seuche is mentioned as identical with the 

 Schweine-seuche, because experimentally the bacillus of Schweine-seuche 

 was found pathogenic for calves, and the Rinder-seuche likewise patho- 

 genic for swine in several instances. 



The bacillus was first observed by Kitt, and further studied by Kitt 

 and Hueppe, and classified as one of the septicaemia haemorrhagica 

 group of organisms. The Italian buffalo disease (Barbone dei bufali) 



