144 



METHODS FOR THE ANALYSIS OF BLOOD 



ALKALI TOLERANCE * 



This method is quite reliable for proving the absence of acidosis, 

 but is not particularly dependable for showing either the presence 

 or the degree of acidosis when it exists. This seems to be due in 

 part to the fact that in conditions associated with acidosis the 

 power of the kidney for excretion of alkalies may be markedly 

 impaired. 



THE RELATIONSHIP OF THE PLASMA BICARBONATE TO ACID 



DIOXIDE 



Corresponding results of 



* Measured either in twenty-four-hour urine or on specimen from shorter period cal- 

 culated to twenty-four-hour basis. 



t After bicarbonate administration likely to indicate more acidosis than is present. 



1 Sellards: Bull. Johns Hopkins Hosp., 1912, 23, 289; Palmer and Hender- 

 son: Arch. Int. Med., 1913, 12, 153; Palmer and Van Slyke: Jour. Biol. 

 Chem., 1917, 32, 499. 



