ALKALI TOLERANCE 



145 



Principle. Sodium bicarbonate is administered in small 

 amounts, either by mouth or intravenously until the reaction of 

 the urine changes from acid to alkalies. The amount of bicarbonate 

 is then noted. 



Procedure. Give (by mouth) 5 gms. of sodium bicarbonate 

 in 100 c.c. of water to the subject under examination. Repeat 

 every half hour until the total bicarbonate administration is 

 equivalent to 0.5 gm. per kilogram of body weight unless the urine 

 becomes alkaline before that time. In case the urine does not 



indirect tests for acidosis 



CARBON DIOXIDE OF ALVEOLAR 

 AIR. 



SODIUM BICARBONATE REQUIRED TO 

 TURN URINE ALKALINE 



t The figures tabulated in this column also indicate the doses of bicarbonate necessary 

 to restore the alkali reserve to normal from acidosis of the severity indicated by the cor- 

 responding plasma COa figures in the first column. 



become alkaline with the above bicarbonate ingestion, continue 

 the administration of the alkali until the urine shows an alkaline 

 reaction. (Because of the likelihood of producing a condition of 



