CHAPTER IX 



INFECTIVE GRANULOMATA GLAND EBS " ACID -FAST " 



BACILLI TUBERCULOSIS LEPROSY THE SMEGMA 



BACILLUS 



CERTAIN diseases are characterised by the formation 

 in the tissues of cellular nodules which resemble granula- 

 tion tissue, and they may usually be transmitted by 

 inoculation of material from the nodules ; hence the 

 conditions are known as " infective granulomata." The 

 principal infective granulomata are, glanders, tuber- 

 culosis, leprosy, actinomycosis and syphilis, and the 

 causative organisms are largely confined to the nodules. 

 Those in which the causative organisms are bacillar in 

 appearance, viz., glanders, tuberculosis and leprosy, are 

 considered in this chapter. 



Glanders 1 



Glanders is a disease which has been known from the 

 earliest times, being recognised by the Greek and Roman 

 writers, by whom it was termed pa\L$ and malleus respec- 

 tively. It is pre-eminently a disease of the horse, mule, 

 and ass, but is also communicable to man and to certain 

 other animals. It is caused by a small bacillus discovered 

 1by Loffler and Schiitz in 1882. 



In the horse the lungs are always affected, and fre- 

 quently the nasal mucous membrane (Fig. 38). Nodules 

 form which afterwards break down and ulcerate, and a 



* See McFadyean, Journ. of State Med., vol. xiii, 1905, pp. 1, 65, 125. 



