HUMAN GLANDERS 357 



muco -purulent discharge appears ; in the older writings 

 the name " glanders " covered only these advanced cases 

 of the disease. In " farcy " the lymphatic vessels and 

 glands are affected, the enlarged glands being known as 

 " farcy buds " (Fig. 39). 



In man the disease is rare, an average of four deaths per 

 annum being caused by it in this country. It occurs in 

 two forms the acute and the chronic. The former is a 



FIG. 38. Nasal septum of glandered horse, showing ulceration of 

 Schneiderian membrane (McFadyean). 



very serious affection, accompanied by high fever, pros- 

 tration, and delirium, and is almost invariably fatal in 

 from two to three weeks ; an eruption closely resembling 

 that of smallpox may appear on the forehead and face. 

 The seat of infection is usually the hand or arm, the nasal 

 mucous membrane being sometimes subsequently involved, 

 and deposits may form in the lymphatic glands, internal 

 organs, and muscles. In the chronic form intramuscular 

 abscesses are frequent from the breaking down of which 

 indolent ulcers may result ; the disease runs a prolonged 



