TUBERCULOSIS 383 



human tuberculosis cervical glands, mesenteric glands (8) 

 lungs and bronchial glands (10), joint and bone disease (9), 

 testis, kidney, etc. grow more luxuriantly in culture 

 than those of Group I, and inoculated into calves and 

 rabbits do not produce the generalised and fatal disease 

 caused by the bovine bacillus, but in rhesus monkeys and 

 in the chimpanzee set up a general tuberculosis. Certain 

 human viruses, differing in certain respects from those of 

 Groups I and II, were also met with and are classed as 

 Group III, but an opinion on their significance is reserved 

 for a future report. 



The Commissioners conclude that the tubercle bacillus 

 in its nutritive and reproductive powers resembles other 

 simple organisms, and that the essential difference between 

 one strain and another depends on variations in these 

 factors, and they classify those bacilli that grow with 

 difficulty on artificial media as dysgonic, and those that 

 grow readily on media as eugonic. There are no definite 

 morphological differences between the human and the 

 bovine types of bacilli. In the rabbit, 10 mgrm. of serum 

 culture introduced by subcutaneous inoculation between 

 the shoulders, induces within 100 days after inoculation, 

 for the human type of bacillus, little or no infection, for 

 the bovine type of bacillus, progressive generalised tuber- 

 culosis and usually death. 



As regards the histological appearances of the tuber- 

 culous process in different animals, Eastwood states that 

 there is an underlying unity of the morbid processes pro- 

 duced experimentally by infection with every variety 

 of bovine and human tubercle bacillus. 



In their final Report, the Commissioners conclude that 

 an appreciable amount of human tuberculosis is caused 

 by bacilli of the bovine type, and that tuberculosis may be 

 communicated to man from infected cow's milk, and from 

 tuberculous meat, either beef or pork. 



