554 A MANUAL OF BACTERIOLOGY 



club -shaped structures, and the disease evidently closely resembles 

 actinomycosis. 



From a case of the white variety Boyce 1 cultivated a strepto- 

 thrix which differed somewhat from the human and bovine 

 Actinomyces, as it grew slower, produced no dark pigment, and 

 on agar formed white raised colonies with radial grooves, not 

 unlike the tiny barnacles found on wooden piles in the sea. Vin- 

 cent 2 also isolated a streptothrix, perhaps identical with that of 

 Boyce, which differed from the Actinomyces in growing feebly in 

 broth, in not liquefying gelatin, and in not being inoculable in the 



FIG. 52. A foot affected with madura disease. (White variety.) 



rabbit. He described it as forming on glycerin agar umbilicated 

 colonies, first white and afterwards red. Shattock 3 suggested 

 that the red, cayenne-pepper-like grains occasionally met with in 

 mycetoma may be due to colonies of the streptothrix which have 

 produced their pigment. Microscopically, this organism (Nocardia 

 indica, Streptothrix or N. madurce, Oospora indica) is identical 

 with the Actinomyces. Musgrave and Clegg in a case of the white 

 variety isolated a streptothrix (8. freeri) differing from the 

 N. indica, but identical with the 8. Eppingeri (Nocardia asteroides). 

 The relation of the black to the white variety of madura disease 



1 HygieniscJw RundscfiMU, 1894, No. 12. 



2 Ann. de VInst. Pasteur, 1893. 



3 Trans. Path. Soc. Lond., vol. xlix, 1898, p. 294. 



