556 A MANUAL OF BACTERIOLOGY 



no means the only organism causing Maduramycosis. Bouffard 

 found an Aspergillus (A. bouffardi) in an African black Madura- 

 mycosis, Pepere in a similar condition in Sardinia, Monosporium 

 scleroiiale, Nicolle and Pinoy in Tunis, Madurella toseuri, and 

 Chalmers and Archibald in the Soudan, Glenospom khartoumensis. 

 There are also white Maduramycoses (i.e. the grains are white), 

 caused by fungi, placed by Brumpt in the genus Indiella, e.g. 

 Indiella mansoni in an Indian form and Indiella somaliensis in 

 India and Somaliland. 



It is difficult experimentally to reproduce mycetoma in animals, 

 but Pinoy has succeeded in doing so with an Aspergillus, and 

 Nicolle with Madurella tozeuri, both in pigeons. 



Mycosis tonsillaris (Mycosis pharyngis leptothricia) 



A chronic disease attacking young adults, resistant to treat- 

 ment, and characterised by the presence of small, white, tough, 

 adherent excrescences on the mucous membrane of the pharynx. 

 Microscopically, the patches consist of collections of epithelial 

 cells and debris, infiltrated with leptothrix filaments and bacteria. 

 The disease seems to be a keratosis, infection with the organisms 

 being secondary. 



But occasionally a true " mycosis " apparently occurs, readily 

 amenable to treatment, and due to a leptothrix. 1 



Leptothrix buccalis 



Four somewhat similar thread forms occur in the mouth, viz. 

 Leptothrix racemosa, L. buccalis maxima, L. innominata, and 

 Bacillus maximus buccalis. The first is very common, forms 

 large threads, shows a peculiar beaded appearance on staining 

 which has been regarded as sporulation, and may be a fungus 

 form. L. buccalis maxima and L. innominata differ from each 

 other in that the former gives a blue granulose reaction when 

 treated with iodine and dilute sulphuric acid, while the latter 

 does not. All these three organisms are very similar, and the 

 filaments are either unsegmented, or the segments are of con- 

 siderable length. The B. maximus buccalis is very like the L. 

 buccalis maxima, but does not give the granulose reaction, and its 



1 See Glasgow Med. Journal, No. 2, 1896, pp. 81 et seq. (Brown Kelly). 



