OTITIS MEDIA 687 



punctate., whitish-grey, translucent colonies on surface agar. 

 On inoculation into animals a specific necrosis was produced. 



Bishop and Ryan, in two out of three cases, isolated an organ- 

 ism which culturally and morphologically resembled the diph- 

 theria bacillus, but which only produced some local inflammation 

 on inoculation into guinea-pigs. In the third case the M. pyo- 

 genes, var. aureus, and the Streptococcus pyogenes were isolated. 

 Guizzetti, and Freymuth and Petruschky have isolated the 

 Klebs-Loffler bacillus in noma. 



OppLER-BoAS BACILLUS. Met with in the stomaoh, particu- 

 larly in cases of carcinoma, and its detection is suggestive of this 

 condition. The bacilli occur in masses, are long and filiform and 

 non-motile, and frequently join one another at an angle. They 

 measure usually 6-8 fi in length, but vary between 3 and 10 /z. 

 The organism is a facultative anaerobe, non-sporing and Gram- 

 positive. It curdles milk and forms lactic acid from various 

 sugars. It is probably the B. bulgaricus. 



OTITIS MEDIA. The Streptococcus pneumonia is perhaps thecom- 

 monest organism met with ; next in frequency comes the Strepto- 

 coccus pyogenes, and then the pyogenic cocci. An influenza-like 

 bacillus is sometimes present (Henry ; see " Meningitis," p. 686), 

 and occasionally the S. mucosus. In scarlatinal otitis media, 

 Blaxall found the 8. pyogenes to be always present, and generally 

 accompanied by other organisms, pyogenic cocci, etc. In thirty- 

 seven cases of mastoid disease Blake found the following organisms, 

 and remarks that as a rule the same were found in the middle ear : 

 Streptococcus . . . . . . .12 



Staphylococcus ....... 5 



Diplococcus (f pneumoniw) ..... 6 



Streptococcus and diplococcus .... 5 



Streptococcus and Bacillus fetidus (f colon bacillus) . 3 

 Streptococcus and Bacillus pyocyaneus ... 1 

 Streptococcus and diplococcus .... 1 



Streptococcus, micrococcus, and diplococcus . . 2 

 In two of the cases no organisms could be isolated. 

 OZ^ENA (ATROPHIC RHINITIS). Lowenberg described in this 

 disease encapsuled bacilli somewhat resembling the pneumo- 

 bacillus morphologically. Some Italian observers found bacilli 

 apparently identical with the diphtheria bacillus. Abel 1 de- 



1 Zeitschr. f. Hyg., xxi, p. 89, 



