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Increased respiration. 



Muscular debility. 



Diminution in bulk of the excretions. 



Functional disturbance of the brain, stomach, &c. 

 Heat is the most essential characteristic of the febrile 

 state, having given name to it in all languages ; this is pro- 

 duced by excessive tissue metamorphosis under the abnormal 

 tension condition of the nerve centres. 



Toxaemia is a term used to indicate poisoning 'of the 

 blood. Certain diseases, more than others, are believed, 

 upon the strongest evidence, to depend upon a chemical and 

 dynamic change in the blood, to which the name of toxaemia 

 is applied. Toxaemia originates at least in two ways : 



1 . By the introduction from without of some morbid poison 



into the blood, as in the case of pleuro-pneumonia 

 and splenic appoplexy in cattle, as well as glanders 

 and other diseases of the horse. 



2. By the non-excretion, and consequent accumulation in 



the blood of post-organic or excrementitious sub- 

 stances, which by their own properties, or the change 

 they undergo, prove injurious to the system. 



All of the zymotic diseases, as well as the exanthematic 

 (smallpox in sheep, for example), have their origin explained 

 by the fact of these modes of blood poisoning. 



The effects of these poisons when introduced into the 

 system of an animal are both local and constitutional symp- 

 toms. The constitutional symptoms, which begin the attack, 

 are nearly alike for them all ; the local symptoms are pecu- 

 liar for each one. 



Toxaemia from non-elimination of the excretions is seldom, 

 if ever, an idiopathic affection. It is therefore best studied 

 in connexion with those diseases of which it forms a second- 

 ary, or resultant, though important part. 



Cachexia is usually understood to mean a depraved 

 habit of system ; an error of development or nutrition affect- 

 ing the general state of the organs and functions with per- 

 version or debility. The history of the different cachexia 

 belongs rather to special pathology. We see instances of this 

 in tuberculosis in cattle, as well as farcy in the horse. The 

 formation of tubercle in the lung and other tissues in the 

 horse on post-mortem examination is very well demonstrated. 



The term "tuberculosis" is applied to certain slow, 

 specific inflammations, abscesses, ulcerations, and other dis- 

 orders of the skin, mucous membrane, glands and bones which 



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