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debility or exliaustioii of tlie nervous system. Its gravity does not 

 depend so much upon the amount of l)k)od ext ravasated as it does 

 upon the disturbance or diminished action of the vasomotor centers. 



Syntpfomt;. — This disease becomes manifested b}' the occurrence of 

 sudden swellings on various parts of the body, on the head or lips, 

 limbs, abdomen, etc. They may l)e diffused or very markedly cir- 

 cumscribed, though in the advanced stages they cover large areas. 

 They pit on jiressure and are but slightly i)ainful to the touch. The 

 limbs may swell to a verj' large size, the nostrils may become almost 

 closed, and the head and throat n\ay swell to the point of suffocation. 

 The swellings not infrequently disappear from one portion of the 

 body and develop on another, or may recede from the surface and 

 invade the intestinal mucous membrane. The mucous lining of the 

 nostrils and mouth is covered with dark red or purple spots, a bloody 

 colored serum ilows from the nostrils, the tongue may be swollen and 

 prevent eating or closing of the jaAvs. In twenty-four or forty-eight 

 hours bloody serum may exude through the skin over the swollen parts, 

 and finally large gangrenous sloughs may form. The temperature is 

 never very high, the pulse is frecxuent and compressible, and becomes 

 feebler as the animal loses strength. A cough is usually i^resent. 

 The urine is scanty and high colored, and when the intestines are 

 much affected a bloody diarrhea may set in, with colicky pains. Some 

 of the internal organs may become implicated in the disease, the lungs 

 may become cedematous, extravasation may occur in the intestinal 

 canal, or effusion of serum into the cavity of the chest or abdomen; 

 occasionally the brain becomes affected. A few cases run a mild 

 course and recovery niixy commence in .three or four days; generalh', 

 however, the outlook is unfavorable. In severe cases septic poison- 

 ing is liable to occur, which soon brings the case to a fatal issue. 



PdHioloyy. — (^n section we find the capillaries dilated, the connect- 

 ive tissue filled with a coagulable or coagulated lymph, and frequentlj'^ 

 we may discover gangrenous spots beneath the skin or involving the 

 skin. The lymphatic glands are swollen and inflamed. Extensive 

 extravasations of blood may be found imbedded between the coats of 

 the intestines, or excessive effusion into the substance of the lungs. 



Treatment. — Diffusible stimulants and tonics should be given from 

 the very start, regardless of fever or frequency of the pulse. Car- 

 bonate of ammonia, 1 dram; fluid extract of red cinchona bark, 2 

 drams, and tincture of ginger half an ounce, with half a pint of water; 

 thin gruel or milk should be given every four or six hours. Sulj^hate 

 of iron in drjim doses may be dissolved in water and given every six 

 hours. Chlorate of i^otassa in 2-ounce doses may be given every eight 

 or twelve hours. When the discharges from the mouth and nose 

 become offensive to the smell, 10 drops of carbolic acid in two ounces 

 of water may be given in a drench, or thrown on the root of the tongue 

 with a syi'inge several times a day. Where the swelling is veiy gi-eat, 



