by poison ivy were afforded, by maaiy cases of acci(ient| and 

 intentional poisoningo The best example of the latter was 

 obtained v/ith. the ether solution from the extraction of the 

 lead precipitate in the Soxhlet apparatus (psige // / of this 

 manuscript). After removing the ether, a small drop of the 

 residue was applied to the wrist as described. An itching 

 red spot about the size of a dime was noticed in thirty-six 

 hours which steadily increased in size. Nearly two days after 

 the application of the poison, a dilute solution of potassium 

 permanganate containing a little caustic potash was rubbed 

 into the spot until the pimples were destroyed. A little 

 black spot was left wherever there had been a pimple showing 

 that the permanganate had been reduced to oxide in the skin. 

 The place was washed and nothing more v/as thought of it until 

 the morning following when it was noticed that the Y/rist had 

 commenoed to swell during the night, and the characteristic 

 watery secretion was running from the poisoned spot. IJore 

 permanganate solution was applied without potash and the 

 wrist was bandaged thinking that this would prevent the spread- 

 ing of the eruption, but it really facilitated spreading by 

 becoming saturated v/ith the poisonous fluid and keeping it 

 in contact with a larger surface of skin. In the meantime 

 the swelling and inflammation had extended nearly to the elbow. 

 The arm now had the appearance of having been bitten by a snake. 



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