58 MICRO-ORGANISMS AND DISEASE. [CHAP. 



Purulent infiltration spread from the seat of inoculation into 

 the subcutaneous tissue ; peritonitis ; spleen much enlarged ; 

 slight pneumonia. A hypodermic syringe-full of the blood of 

 this animal was injected under the skin of a second rabbit, 

 and this died after forty hours. Post-mortem examination 



> v 



-n 



FIG 26. FROM A PYOGENIC MEM- 

 BRANE COVERING THE SEROUS COAT 



OF THE INTESTINE OF A BABBIT 

 DEAD OF PY^KMIA. 



1. A large oval nucleus, probably the 



nucleus of a detached endothelial 

 cell. 



2. A pus corpuscle. 



The rest of the pyogenic membrane 

 is beset with small micrococci. 



FIG. 27. PYAEMIA OF RABBIT. 



Blood of spleen. Between red blood- 

 discs three dumb-bells and two 

 single micrococci are shown. 

 (Gentian violet staining. ) 



[The micrococci as here represented 

 are somewhat too large. ] 



showed the same lesions as in the first case. In the blood- 

 vessels of the affected parts were present micrococci, single, as 

 dumb-bells, and in zooglcEa ; they were spherical, about 

 0'00025 mm. in diameter, (d) Micrococcus causing septicaemia 

 in rabbits. An infusion of meat was prepared ; this was left 

 to putrefy, and of this fluid a quantity was injected under the 

 skin of the back in two cases. Extensive gangrene with much 



FIG. 28. OVAL MICROCCCCI FROM THE BLOOD-VESSEL OF THE SPLEEN OF A 

 RABBIT, DEAD OF KOCH'S SEPTICAEMIA. 



oedematous exudation followed, and death ensued in two days 

 and a half. The blood, the capillaries of the kidney, and the 

 enlarged spleen, contained numerous oval micrococci. Two 

 drops of the cedematous exudation-fluid were injected under 

 the skin of the back of another rabbit. Death followed in 

 twenty-two hours. There was no gangrene here ; but cedema 



