86 MICRO-ORGANISMS AND DISEASE. [CHAP. 



(<-) Bacillus of typhoid fever of man. Klehs 1 described in 

 the inflamed PeyePs glands, in the mesenteric glands, larynx, 

 and lungs of patients dead of typhoid fever certain bacilli, 

 which are about 0'0002 mm. thick and of various lengths, 

 forming filaments up to 0*05 mm. long. These bacilli form 

 spores. Eberth 2 found in about 50 per cent, of cases of 

 patients dead of typhoid fever, in the mesenteric glands and 

 spleen, peculiar short bacilli, rounded at their ends, and 

 occasionally slightly constricted in the middle ; some of them 



FIG. 51. FROM A SECTION THROUGH THE MESENTERIC GLAND OF A PERSON 

 WHO DIED OF TYPHOID FEVER. 



1. Capillary blood-vessel filled with blood-corpuscles. 



2. Large lymph-cell. 

 8. Nuclei. 



4. Bacilli. 



Magnifying power 700. 



contained spores. The bacilli stain very freely with methyl- 

 violet. It is, however, doubtful whether these bacilli can 

 be considered as necessarily and intimately connected with 

 typhoid fever, seeing that they are not constant, and only 

 occur in the mesenteric glands and spleen, i.e. in localities into 

 which an immigration of putrefactive bacilli from the bowels 

 may easily take place ; especially when we remember that in 

 cases of typhoid fever that end fatally there constantly occur 

 severe sloughing and necrosis of the mucous membrane of the 

 Peyer's glands. The bowels in typhoid fever always contain 

 innumerable masses of micrococci in colonies ; and these 

 micrococci are found not only in the tissue of the intestinal 



1 ArcUvf. exp. Path. vol. xii. 



2 Virchow's Archiv, vols. Ixxxiii., Ixxxvii. Fee also Koch, Mitthcil. a. d.k. 

 Gemindheitsamte, i. 1881 ; and Gaffky, ibid. lSt-2. 



