88 MICRO-OKGANISMS AND DISEASE [CHAP. 



partaken of beef and ham sandwiches sold at Welbeck on the 

 occasion of a sale of timber and machinery on the estate of 

 the Duke of Portland. The infection showed itself after an 

 incubation-period varying from twelve hours or less to forty- 

 eight hours or more. The first symptoms were a sadden 

 feeling of languor, nausea, griping in the abdomen, in some 

 cases giddiness and fainting, and pain in the trunk. Then 

 followed pain in the abdomen, diarrhoea, and vomiting, the 

 diarrhoea being most constant. Four cases ended fatally. 

 On post-mortem examination enteritis and pneumonia were 

 most prominent. Part of the kidney was examined in 

 microscopic sections, and it was found that many of the 

 tubuli uriniferi contained hyaline casts ; that the capillaries of 

 the glomeruli of the Malpighian corpuscles, and the afferent 

 arterioles, contained numbers of bacilli, some of the capillaries 

 being distended by and plugged with masses of bacilli densely 

 aggregated. In February, 1881, a- similar but less extensive 



FIG. 53. ISOLATED BACILLI IN A SMALL ARTERY OF THE SAME KIDNEY 



AS IN PRECEDING FIGURE. 



Some bacilli contain spores. 



outbreak occurred at Nottingham, among fifteen persons 

 that had partaken of certain baked pork. The symptoms 

 were similar to those in the Welbeck outbreak. One case 

 ended fatally. Post-mortem : bloody exudation in pericardium, 

 intense pneumonia, mesenteric glands enlarged, enteritis, 

 Peyer's glands enlarged. Bacilli similar to those of the above 

 case were found in the blood, in the pericardial exudation, in 

 the juice and in the bloody fluid filling the alveolar cavities of 

 the inflamed lung, in the vessels of the kidney, in the 

 submucosa of the inflamed Peyer's glands of the small intestine, 

 in the blood-vessels of the spleen and around them. 



The bacilli vary in length between 0'003 and 009 mjn. ; 

 their thickness is about O'OOIS mm. They are rounded at 

 their extremities, single or in chains of two, and some contain 

 a bright oval spore, situated in the centre or at one end, and 

 about O'OOl mm. thick. This was the case with the bacilli 

 in the glomeruli of the kidney of the Welbeck case. The 



