THE CONNECTIVE TISSUES. 51 



between the matrix of bone and cartilage, and the cells of 

 those tissues. 



Waldeyer* especially endeavoured to confirm these views, in 

 the case of bone, by his beautiful researches on the process of 

 ossification. It is obvious that, in the event of the above- 

 described mode of development being demonstrated in the 

 several cases of bone, cartilage, and connective tissue, a similar 

 genetic agreement for all these tissues, though undoubtedly in 

 a different sense, from that advanced by Virchow, would also 

 be obtained. But to what extent satisfactory replies have been 

 given to these questions will hereafter receive consideration 

 when these tissues are severally described. 



As observers gradually acquired these views respecting the 

 histogenesis of the connective tissue substances, a new starting- 

 point for important general considerations respecting the living 

 processes taking place in connective tissue was obtained, in 

 quite another mode, by the investigation of living connective 

 tissue. Yon Recklinghausen'f' demonstrated that, in living con- 

 nective tissue, cells are present which agree in their characters 

 with the white blood corpuscles (lymph or pus corpuscles), and, 

 in consequence of the amoeboid movements they are capable 

 of performing, constantly change their situation in the tissue. 

 Von Recklinghausen further proved that when suppuration 

 occurred in connective tissue, in opposition to the doctrine pro- 

 pounded by Virchow of the formation of pus by multiplication 

 of the tissue cells, a migration of these movable cells from 

 without into the substance of the tissue must be admitted to 

 take place. These facts have attracted a proportionately greater 

 interest since Strickerf established the permeability of the walls 

 of the vessels for red blood corpuscles. Cohnheim, indeed, 

 has recently referred to the older observations of Waller || on 

 the relation of the white blood corpuscles in inflammation, 

 which have hitherto remained unnoticed; and, supported by these 



* Archiv fur Mikroskopische Anatomie, Bd. i., p. 354. 

 t Virchow's Archiv, Bd. xxviii., p. 157. 

 { Sitzungsberichte der Wiener Akademie, Bd. Hi., p. 379. 

 Virchow's Archiv, Bd. xl., p. 1. Kosinksi, Wiener Med. Wochen- 

 schrift, No. 56 and 57, 1868. 

 || Philosoph. Mag., Vol. xxix. 



