168 STRUCTURE OF THE NERVOUS SYSTEM, BY MAX SCHULTZE. 



constituting terminal organs of the sensory nerves. These are 

 most commonly found in man in the subcutaneous connective 

 tissue of the sides of the fingers and toes, seated on the volar and 

 plantar nerves; also on the nerves supplying joints, and in the 

 nerves coursing between various muscles of the trunk and 

 extremities ; * in animals, however, they are found in many 

 other parts of the body, and may be most easily obtained 

 for examination from the mesentery of the cat. Each of these 

 corpuscles receives a medullated nerve fibre, which does not 

 again emerge from it. The corpuscle itself consists of many 

 concentrically arranged layers of connective tissue, becoming 

 always more closely packed near the centre, and surrounding 

 a cavity filled with soft abundantly nucleated and very easily 

 alterable material, which undergoes coagulation after death, and 

 into the interior of which the nerve fibres penetrate. These, 

 after they have lost the medullary sheath and the sheath of 

 Schwann, which becomes continuous with the laminated sheaths 

 of connective tissue investing the corpuscle, consist only of the 

 axis cylinder, which terminates in a little bulb.-|- Dr. Grandry, 

 who has examined the Pacinian corpuscles with higher magni- 

 fying powers than appear to have been previously employed, 

 observed a very distinct fibrous structure in the axis cylinder in 

 their interior, and also that the terminal bulbs consist of finely 

 granular substance, from which the diverging terminal fibrils 

 may be clearly distinguished. Closely allied to the foregoing 

 are the numerous terminal nerve corpuscles described and 

 depicted by Krause as existing in the conjunctiva, the genitals, 

 and other parts of the body, which differ from the Pacinian 

 corpuscles only in the absence of a thick laminated investment.* 



* See Rauber, Untersuchungen uber das Vorkommen und die Bedeutung 

 der Vater'schen Korper, " Researches on the Distribution and Function of 

 the Corpuscles of Vater," 1867. 



f See the numerous illustrations of these corpuscles and their minute 

 microscopic anatomy in Henle and Kolliker's Essay, Ueber die Pacini'scfien 

 Korper an den Nerven des Menschen und der Saiigethiere, Zurich, 1844, 

 which was followed by the work of Herbst, entitled Die Pacini'sche 

 Korper und Hire Bedeutung, Gottingen, 1848. There are numerous recent 

 investigations on the point, amongst others, those of Leydig, Krause, 

 Kolliker, and Rauber. 



| See W. Krause, Die terminalen Korperchen, 1860 ; Anatomische 



