356 THE SPLEEN, BY WILHELM MULLER. 



exhibiting amoeboid movements (Cohnheim). There may be 

 frequently found in the splenic pulp, especially in adult animals, 

 large cells which either contain granular pigment presenting 

 the characters of Hsematoidin, or rounded bodies resembling 

 coloured blood corpuscles. We may presume that the greater 

 number of these cells containing blood corpuscles are occasioned 

 by the migration of coloured blood corpuscles into the proto- 

 plasm of the adjoining pulp cells. 



The cells of the pulp are connected with one another by 

 means of an intercellular substance. This was first observed 

 by Tigri, and was more minutely described by Billroth. When 

 examined in the fresh state, this appears as a pale, feebly refract- 

 ing, very finely granular, tenacious substance, forming a deli- 

 cate network between the protoplasm of the several cells. In 

 chromic acid preparations it assumes the character of a tissue 

 composed of homogeneous intercommunicating fibres. 



At the periphery of the Malpighian corpuscles it becomes 

 continuous, without any sharply defined line of demarcation, 



Fig. 65. 



Fig. 65. From the spleen of the Hedgehog. , a M alpighian cor- 

 puscle, with its vascular apparatus ; b, splenic pulp, with the interme- 

 diary blood passages ; c, the rootlets of the veins. 



with the intercellular substance of the cortical layer. Near 

 the capsule of the spleen, and also near the terminations of the 

 capillaries and the origins of the veins, the intermediate sub- 

 stance becomes more strongly refractile as regards light, and 

 more distinctly fibrillar. It here becomes continuous on the 



