392 THE BLOOD, BY ALEXANDER ROLLETT. 



corpuscles in the immediate neighbourhood of the metallic 

 electrodes ; those observed at the positive pole being similar 

 to those effected by acids, and those of the opposite pole to 

 those of the alkali which is there set free * We shall hereafter 

 enter more fully into the action exerted by acids and alkalies 

 on the corpuscles. 



6. After Klebs,f Kollett,J and Beale had originally de- 

 scribed the influence of increased temperature on the red 

 blood corpuscles, Max Schultze || first applied a more exact and 

 methodic mode of investigation by means of the slide he has 

 constructed, which is capable of being heated to a definite degree. 



At about 52 C. (125 F.) the red corpuscles of man present 

 first shallow and then deep fissures, which ultimately lead to 

 the detachment of spherical masses. Some blood corpuscles 

 assume various shapes, or thrust forth moniliform fibres. The 

 latter forms immediately remind one of those found by Bind- 

 fleisch and Preyer in extravasated blood. Finally, spheroidal 

 coloured drops are always found, so that the middle part of the 

 original corpuscles corresponds to one of the larger of such 

 fragments, which, varying in magnitude from this- to an almost 

 molecular fineness, are beset with smaller particles at their 

 margin, or are surrounded by a series of them in a free state. 

 The alterations described by Klebs as occurring at a tempera- 

 ture of 38C. (100 F.) were not observed by Max Schultze. From 

 observations made in a water bath, Rollett ascertained the 

 temperature at which the blood corpuscles became spheroidal 

 to be between 40 and 50 C. (104 122 F.) The changes in 

 the corpuscles, however, do not occur suddenly, but only after 

 long exposure, and without the segmentation observed at 52 

 C. (125 F.) 



Lake-coloured blood, according to Max Schultze, is first ob- 

 tained when the temperature is raised to 60 C. (140 F.) 



* Rollett, loc. cit., Band xlvii., p. 359 ; Band Hi., p. 257. A. Schmidt, 

 Virchow's Archie, Band xxix., p. 29; Hamatologische Studien. Dorpat, 

 1865, p. 116. Neumann, Refchert and Du Rois' Archiv, 1865, pp.682 690. 



t Centralblatt fiir die medicin. Wissenschaften, 1863, p. 851. 



J Loc. cit., Band 1., p, 192. 



Loc. cit. 



i! Loc. cit., p. 1. 



