THE CORRELATION OF THE INTERNAL SECRE- 

 TIONS IN REGARD TO THEIR GENITAL 

 FUNCTIONS 



I have endeavoured to trace, for the most part from 

 my own observations, the disjointed facts concerning 

 the influences exerted by the different members of the 

 hormonopoietic gland system upon one another, on the 

 genital organs and on the metabolism generally, in so far 

 as the reproductive system may be concerned ; and in so 

 doing I have in some cases been able clearly to show the 

 nature of the associations between the different organs. 

 It is, however, absolutely impossible at the present time 

 to correlate fully all their functions ; but in view of what 

 was said at the commencement as to the necessity for a 

 lead in this intricate matter, I cannot refrain from 

 enunciating what I believe to be the general principles. 

 I shall not further analyse the details. 



It appears, from the evidence at our disposal, that in 

 spite of great variations in the structure of the hormono- 

 poietic glands in different mammals, the total func- 

 tional result is the same so far as the genital processes are 

 concerned. The variations in function that depend 

 on the differences of structure are probably related to 

 differences in the food and habits of life ; and in adapting 

 our knowledge to the requirements of human physiology 

 we must take into account both the essential functions 

 to which we have already referred — the individual 

 metabolism of the mother, and the metabolism of her 

 reproductive functions — for they are completely inter- 

 dependent in normal circumstances. 

 The functions We have seen as the result of our studies that the 

 of the ovaries, ovaries, on the one hand, have as their share of these 



Total 

 functional 

 result of 

 internal 

 secretions. 



