NEURO-EPITHELIAL CELLS 25 



plasm and is often flattened against the basement membrane, the 

 amount of flattening being proportionate to the volume of its 

 mucous content. 



The accumulation of mucinogen within its cytoplasm expands 

 the cell, finally ruptures its wall in the direction of least resistance, 

 and thus permits its mucous content to exude upon the free surface, 

 leaving behind the small granular protoplasmic cell remnant at- 

 tached to the basement membrane. The further history of these 

 cell remnants is somewhat doubtful. They are possibly absorbed, 

 removed, and finally replaced by mitotic division of adjacent cells. 

 There is, however, some evidence to show that they are still 



FIG. 24. GOBLET CELLS AS SEEN IN A 

 TBANSECT10N OF A CRYPT OF THE LARGE 

 INTESTINE OF MAN. 



Sections of five goblet cells are seen 

 among the columnar cells which line the 

 tubule. Muchematein and eosin. x 550. 



FIG. 25. DIAGRAM SHOWING THE ARRANGE- 

 MENT OF THE COLUMNAR AND GOBLET 

 CELLS OF THE PRECEDING FIGURE. 



The goblet cells are represented as being 

 empty ; their unaltered basal portions con- 

 taining the nucleus are distinctly seen. 



capable of further growth, whereby they may regain their original 

 form and become again capable of passing through the same 

 stages of secretory activity. 



NEURO-EPITHELIAL CELLS. These cells are derivatives of 

 columnar epithelium which are specially differentiated to form 

 nerve end-organs. They are usually elongated cells having a 

 bulging nucleated center, their free extremity either projecting 

 beyond the epithelial surface as a bundle of fine cilia or as a 

 slender non-ciliated process which terminates within a pore-like 

 opening directly connected with the free surface. Their at- 

 tached extremity, tapering to a fine process, is in relation with 

 the terminal arborization of the axis cylinder of a nerve fibre. 

 Neuro-epithelium is found only in the several organs of special 



