82 



NORMAL HISTOLOGY. 



The latter are derived from the subdivision of two or three fibres that, after 

 losing their medullary coat, enter near the base of the corpuscle. The 

 fibrillae are beset with varicose enlargements and club-shaped terminal 

 swellings. The fibrous capsule consists of several connective tissue lamellae, 



possessing flattened nuclei, and encloses the semi- 

 fluid or granular substance in which the end-arbor- 

 izations are embedded. 



In contrast to the foregoing end-organs, in 

 which the axis-cylinder subdivides into numerous 

 terminal threads disposed 

 as more or less elaborate 

 intertwinings, a second 

 group is distinguished by 

 the presence of a lamellated 

 capsule that encloses a cyl- 

 indrical core, the inner buld, 

 containing the slightly 

 branched axis-cylinder. 

 These endings, of which 

 the Pacinian corpuscle is 

 representative, are rela- 

 tively large and occur chiefly in the skin and the serous membranes. 



A transitional form, connecting them with the spherical end-bulbs, is 

 the cylindrical end-bulbs. These are found in various parts of the 

 corium, the oral mucous membrane, and between the bundles of striped 

 muscle and of tendon. They are irregularly cylindrical, often somewhat 

 bent, and consist of a thin lamellated capsule that encloses a core of semi- 

 fluid substance in which is the centrally placed axis-cylinder. The latter, 

 after losing the medullary coat on entering the proximal pole of the cor- 



FIG. 114. Genital corpuscle 

 from integument of penis ; nerve 

 divides before piercing capsule 

 and terminates in intricate end- 

 windings. (Dogiel.) 



FIG. 115 Genital cor- 

 puscle from integument 

 of human clitoris. X 350. 

 ( Worthmann. ) 



FIG. 116. Cylindrical end-bulbs attached to sensory nerves in parietal peritoneum of man. (Dogiel.) 



puscle, traverses the core with little or no branching until near the distal 

 pole, where it ends in a single or slightly subdivided terminal enlargement. 

 The Vater-Pacinian Corpuscles. These structures, also called the 

 lamellated corpuscles, are large ellipsoidal bodies, from .51.5 mm. in length 

 and about one-third as much in breadth, situated within the connective tissue 

 in many parts of the body. In man they are found in the deeper layer of 

 the corium, especially in the skin covering the palmar and plantar aspects 

 of the fingers and toes and the nipple, in the connective tissue in the 



