620 MEDICINES. 



Babes, Hellmann, Pilavios and others state that they have cured 

 early cases of glanders by injections of mallein at intervals of 

 three or four days, until the mallein ceases to cause reaction, 

 Pilavios says that this treatment hastens death in advanced cases 

 of the disease. Bonome mentions that an affected man was cured 

 by mallein after a six weeks' course of treatment. 



Professor McFadyean (" Journal of Comp. Path.," March, 

 1900) treated a glandered gelding, one of whose hind legs 

 was much swollen and had farcy buds on it, by repeated injections 

 of very large doses (up to 100 times the usual quantity) of mallein, 

 with the result " that this horse, although showing external sym- 

 toms of farcy, became quite cured (or recovered). Afterwards, 

 when inoculated with virulent glanders bacilli, it again contracted 

 the disease, and it had again recovered before it died from 

 another cause." Although these facts may not be absolute proof, 

 they are very strong reasons for assuming, that mallein, especially 

 in very large doses, has a curative influence on glanders. We 

 know that reacting horses sometimes develop outward symptoms 

 of glanders, during a course of ordinary doses of mallein, after 

 tliey have been tested even half a dozen times. 



Mercury. 



Biniodide of Mercury 



is chiefly used in the form of absorbent ointment, which is 

 usually made as follows: — 



Biniodide of mercury ... ... ... 1 part. 



Lard or vaseline ... ... ... ... 4 to S parts. 



In hot climates, the amount of the vaseline or lard should be 

 double that used in cold countries. The irritating effect of 

 biniodide of mercury passes off quicker than that of cantharides. 



Veterinary-Surgeon Desmond tells me that the addition of 5 per 

 cent, of the hydrochloride of morphine to biniodide of mercury 

 ointment, greatly diminishes the irritation which that application 

 sets up. 



Cadeac states that the antiseptic action of biniodide of mercury 

 is 34 times greater than that of corrosive sublimate. He recom- 

 mends its use in the following antiseptic solution : — 



Biniodide of raercurv... ... ... ... I part. 



Alcohol " ... 200 parts. 



Water 10,000 „ 



This solution has the advantage of not hurting the hands or 

 instruments. 



