64 VETERINARY HOMCEOPATHY. 



sion to the following opinion in the ''Journal of Comparative 

 Pathology and Therapeutics'" for March, 1S93, "^'i^- 



' ' The very numerous observations that have now been pub- 

 lished at home and abroad regarding the action of- Mallei ?i appears 

 to warrant the following conclusions: 



1. " If in any horse that presents symptoms exciting a sus- 

 picion of glanders or that is known to have been exposed to the 

 infection of glanders, an injection of Mallein raises the tempera- 

 ture from about the normal (under 10 degrees) to 104 degrees 

 and produces a marked inflammatory reaction at the seat of in- 

 jection that horse may be pronounced ' glandered.'' 



2. "If in such a horse an injection of Mallein determine a 

 marked local reaction and an elevation of temperature equal to 2 

 degrees, that horse may be pronounced ' probably glandered.' 



3. " In horses that have already a febrile temperature (102 de- 

 grees or over) the temperature reaction after Mallei?i is inconstant 

 and unreliable as a guide to diagnosis. 



"It only remains to be added that the local reaction deserves 

 to be called ' marked' when the swelling extends for three or four 

 inches from the point of injection." 



It is now necessary to explain for the right understanding of 

 the reader that Mallein is prepared by what is called cultivating 

 the virus (poison) of a glandered horse, the virus being found in 

 the discharges from the nose and eyes and this is cultivated from 

 one growth to another in the Pathological Laboratory until it is 

 sufficiently attenuated for use, and may be obtained sometimes in 

 the fluid form and sometimes in the dry as is exemplified by what 

 is described as Foth's ' Dry Mallein ' nor does there appear to be 

 any difference in the reaction of the two samples; presumably 

 the dry sample keeps the best. The usual quantity used at one 

 inoculation is 2J2 cubic centimetres of the fluid preparation which 

 should be injected with a chemically clean subcutaneous syringe 

 that has been rendered properly aseptic under the skin of the 

 neck; probably no better method of rendering the syringe aseptic 

 can be adopted than plunging the various disconnected parts into 

 boiling water and there holding them for a few minutes, after 

 which they can be put together and used; the middle part of the 

 neck measuring both the length and depth of same, is the best 

 place to select for the operation; this of course is the point where 



