KALA-AZAR 



the dogs. These observations have been fully confirmed 

 by other investigators. 



CANINE LEISHMANIA. The course of the disease is com- 

 paratively mild, though there may be a certain amount 

 of pyrexia and emaciation. The parasites may be found 

 in large numbers in the liver, in the spleen, and in the 

 bone-marrow. A considerable proportion of dogs have 

 been found infected naturally, though the proportion 

 varies both according to district and according to season. 



Whether the disease in man is derived from dogs is 

 at present unknown. It is possible that they form the 

 reservoir, and some experiments show that Pitlex serra- 

 ticeps, which will occasionally feed on man, can serve 

 as a carrier of the disease, as parasites develop in these 

 fleas. Attempts to infect dogs with the parasites of kala- 

 azar in India have failed. 



