262 



APPENDIX. 



I. NOTABLE DATES. 



Malaria. Discovery of the parasites, Laveran, November 6, 

 1880. Differentiation of species and asexual life-cycle, Golgi 

 and others, autumn of 1885, and onwards. Conjugation of 

 sexual forms, McCallum, 1897-8. Sexual cycle, Ross, 1897-8. 



Redwatev Fever. Piroplasma discovered by Babes in 1888. 

 Mode of transmission, Smith and Kilburne, 1893. 



Yellow Fever. Mode of transmission of yellow fever, Reed 

 and Carroll, U.S. Army Commission, 1900-1. Mild form 

 recognized, 1841. 



Trypanosomes. In fish, Valentine, 1841. In frogs, Gruby, 

 1843. In rats, Lewis, 1878. As a cause of disease (surra), 

 Evans, 1880. As a cause of disease (nagana), Bruce, 1894. 

 In man Nepveu described a trypanosome, 1890, but the 

 description was not conclusive. In man Ford discovered and 

 Dutton described T. gambiense, 1901. In man, in sleeping- 

 sickness, Castellan! discovered the same trypanosome in the 

 cerebrospinal fluid, 1902. 1908, Kleine showed that after 

 Glossina have fed on an infected man in fifteen days or more 

 the fly is infective. 



Spivochata obermeieri or Spirochata recurrent is t discovered by 

 Obermeier, 1873, named 5. rec^trrentis, 1874, an< ^ $ obermeieri, 



1875- 

 Spirochata duttoni. P. Ross, 1904. Nabarro had previously 



reported this discovery, but report was not published till after 

 Ross's. 



Spirochata pallidum or Treponema pallidum. Schaudinn, 

 spring of 1905. Spirochatapertenuis. Castellani, June, 1905. 

 Spirochaeta in granuloma pudendi, Wise, 1906. 



Leishman- Donovan Bodies. Leishman and Donovan indepen- 

 dently in kala-azar, 1903. In Delhi boil, Wright, 1903. 

 Rogers proved their flagellate stage, 1904. 



