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sound and of a just size, the right was about four times as big, distended like a blown 

 bladder, and yielding as if full of pap ; he having often passed a wheyish liquor after his 

 urine, during his illness. Upon opening this kidney, we found it quite full of a white 

 chalky matter, like plaster of Paris, and all the fleshy substance dissolved and worn away, 

 by what I called a nephritick cancer. This had been the source of all his misery ; and 

 the symptomatick vomitings from the irritations on the consentient nerves, had quite 

 starved and worn him down. I have narrated the facts, as I saw and observed them 

 deliberately and distinctly, and shall leave to the philosophic reader to make what 

 inferences he thinks fit ; the truth of the material circumstances I will warrant." 



But perhaps his investigations on the senses are those best known. 

 Rudolph Wagner's Handwbrterbuch der Physiologie (1842-53) contains 

 essays from the pen of the then most renowned physiologists. It 

 was the successor of Todd's Cyclopaedia of Anatomy and Physiology 

 (1836-59). His collected works were published in 1851. There will 

 be found his important observation on glands. In the Handworterbiich 

 one finds Weber's classical contributions to Tastsinn und Gemeingefiihl 

 or Touch and Common Sensation, Vol. III., 2. 481 (1846). 

 Psychology was, largely through his investigations and those of the 

 Leipzig School, put upon a physiological basis. " Weber's law " and 

 " Fechner's law " are significant of the important part played by the 

 direct estimation of physiological facts in their bearing on psycho- 

 logical phenomena ; they indicate where physiology and psychology 

 touch, over-lap, and in fact integrate. 



ED. FR. WEBER, of Halle, a younger brother (1806-1871), 

 wrote the article Muskelbewegung in Wagner's Dictionary, 

 and jointly with a still more famous brother, Wilhelm, 

 Mechanik d. mensch. Geh- Werkzeuge (Gottingen 1836), which includes 

 an analysis of locomotion and intricate studies on the mechanism of 

 joints. It is a far stride from the Webers to Professors E. J. Marey 

 and J. Chauveau, both of Paris, still happily amongst us. It was just 

 this question of the study of the pulse that led up to Marey's method of 

 transmission of movement in air. The study of the pulse could only 

 be taken up scientifically after Weber had developed his doctrine 

 (1850) of the theory of waves in elastic tubes, and after KARL VON 

 VIERORDT (1818-1884) had invented his sphygmograph, albeit a 

 heavy equipoised system of levers with a button resting on the radial 

 artery. (Die Lehre v. Arterienpuls, &c, 1855.) Settling first as a 

 physician in Karlsruhe, Vierordt's works on carbonic acid, in 

 respiration, and his article Respiration in Wagner's Handworterbuch 

 (1846) brought him the Chair of Physiology in Tubingen. He was 

 one of the earliest to enumerate the blood corpuscles, he founded 

 sphygmography, used largely spectroscopic analysis for physiological 

 purposes, and in all published over one hundred memoirs. 



