28 NORMAL HISTOLOGY. 



line of the equator of the nucleus ; this gradually 

 deepens and by the time the daughter-nuclei have 

 reached the rosette stage it has completely divided 

 the cell-body forming the daughter-cells. It is pos- 

 sible that in this form of cell-division the process 

 may be varied, and that some of the above- 

 described changes in the intranuclear network may 

 be modified or omitted. 



Other forms of cell-multiplication are described. 

 Direct cell-division or Amitosis, in which the above 

 changes in the nuclear network do not take place ; 

 the nucleus and cell-body are separated into two 

 parts by simple constriction. The process of 

 budding or germination, in which the cell-body sends 

 off a bud-like process, which becomes nucleated and 

 is then set free by a constriction of its pedicle. 



A mode of division, called endogenous cell-repro- 

 duction, is described, in which the division is said to 

 occur entirely within the membrane of a cell, called 

 the parent-cell, so that the new organisms the 

 daughter-cells are not at once set free. This mode 

 of cell-division is, however, doubtful, or at least ex- 

 tremely infrequent. These modes of cell-reproduc- 

 tion seem to be different, and yet there is much 

 reason for believing that they are really only modi- 

 fications of one process ;, but in the present condition 

 of our knowledge on the subject, all general state- 

 ments should be very cautiously made ; and such 

 classifications as the above are to be regarded merely 



