THE GASTROINTESTINAL CANAL. 153 



same way as the solitary nodules with blood and 

 lymphatic-vessels. 



THE LARGE INTESTINE. 



The mucosa of the large intestine is thickly set 

 with tubular glands similar to Lieberkuhn's glands 

 in the small intestine, but is destitute of villi. Soli- 

 tary lymphatic nodules are abundant, and are, as a 

 rule, somewhat larger than those of the small in- 

 testine. The distribution of blood- and lymphatic- 

 vessels resembles in most respects that described in 

 the stomach and small intestine. 



TECHNIQUE. 



Sections of Stomach. Bits of perfectly fresh rabbit's or 

 dog's stomach, from the fundus and the pyloric region, 

 should be stretched on a bit of cork to prevent shrink- 

 age, and immersed in absolute alcohol. After twenty- 

 four hours the fluid should be changed, and in three or 

 four days the specimen will probably be hard enough to 

 cut. After imbedding in celloidin, sections from both 

 regions are made perpendicular to the surface, stained 

 double and mounted in balsam. The nuclei of all the 

 cells are stained violet by the haematoxylin ; in the pep- 

 tic glands the bodies of the granular peptic cells are 

 stained a deep rose-red, while the others are but slightly 

 colored, or not at all. Sections perpendicular to the 

 surface of a stomach, whose blood-vessels are filled with 

 the mixture of Prussian blue and gelatin, and stained 

 with carmine, are very instructive. 



