82 LOCALIZED INFECTIONS OF PUS NATURE 



watery solution. In pus a considerably longer time is 

 required. 1 to 20 carbolic kills in one minute; 1 to 

 500 in about one-half hour. The pus in which the 

 staphylococcus lives supplies a protective envelope, 

 and should be well mixed and diluted with the germi- 

 cide. 



This organism is very virulent for the smaller animals, 

 which may be affected even by rubbing on, or injection 

 under, the skin. It will then produce a local abscess 

 or septicemia. It may produce acute inflammation 

 of the interior of the heart or bone disease. 



Staphylococcus Pyogenes Albus. The Staphylococcus 

 pyogenes albus is precisely like the foregoing except 

 that it does not produce the golden yellow pigment, 

 but grows in a porcelain-white manner. There is an 

 organism on the skin to which we give the same 

 name, but add the word "epidermidis." It is con- 

 stantly present on the surface, in the epidermis and in 

 the glands of the skin. Since its pus-forming ability 

 is so feeble, "pyogenes" may be omitted and the 

 name Staphylococcus epidermidis albus given. It does 

 not produce disease, but is of constant annoyance in 

 making blood cultures. Another staphylococcus pro- 

 duces a lemon-yellow color. 



Opsonic Index. The use of killed bacteria to produce 

 an increased resistance against an existing infection 

 has already been discussed. This method of treat- 

 ment is particularly suitable for infections with these 

 staphylococci. The procedure is about as follows: 

 Cultures are made from the diseased part, grown in 

 large quantities on laboratory media, washed off, 

 suspended in physiological salt solution and heated to 



