180 LOUIS BAUMAiST 



is probably derived from creatin, that is, u definite percentage of tho 

 body creatin is daily converted into creatinin. The creatinin excretion is 

 proportional to tho bulk of active muscle tissue. The daily amount of 

 creatinin excreted by a given individual is constant under widely varying, 

 conditions. It is increased (luring fever and diminished during starvation 

 and during periods of muscle disintegration. 



Creatinin is eliminated by the kidneys with great facility and is only 

 retained in the blood in advanced disease of the kidneys. When creatinin 

 is fed or injected it is almost quantitatively eliminated, whereas creatin 

 under similar circumstances is largely destroyed in the body. 



