Tli ARTHUR ISAAC KENDALL 



Summary and Conclusions 



Other infectious diseases of the digestive tract of the toxicogenic type, 

 as paratyphoid fever, Asiatic cholera, coll colitis, and invasion by the 

 meat poisoning bacteria, are equally available for carbohydrate therapy. 

 The general principle involved is the same. The objectives to be attained 

 are: 



1. The establishment of a lactic acid [fermentative] intestinal 



flora in which Bacillus acidophilus or Bacillus bifidus, or 

 both, become dominant. - 



2. The shifting of the metabolism of the normal, facultatively 



proteolytic organisms to the fermentative side. 



3. The shifting of the metabolism of the invading organism from 



the toxicogenic [proteolytic] to the fermentative side. 



4. To be certain that organisms productive of abnormal fermen- 

 v ...; . tative products, as gas bacilli, are not resident in the 



intestinal tract in numbers sufficient to become offensive 

 when the carbohydrate regimen is established. 



5. To administer carbohydrate in amounts and at intervals suf- 



ficient to keep the entire digestive tract, and particularly 

 the lower levels, continuously permeated with the requisite 

 amount and kind of sugar. 



Properly carried out, this bromatherapeutic method of specifically 

 influencing infection will result in several important contributions to the 

 welfare of the patient. 



The reestablishment of a normal acidogenic flora will create intestinal 

 conditions unfavorable to the development of those invaders which are in 

 the alimentary canal. 



The fermentative shifting of the metabolism of the members of the 

 facultative group will prevent the formation of inclol and other bacterial 

 decomposition products of !he ammo acids. This will lessen materially the 

 work of the liver. 



The fermentative shifting of the metabolism of the invading organism 

 will make it potentially a lactic acid bacilhis in place of a toxicogenic 

 organism. The abundant supply of carbohydrate will tend to reduce the 

 loss of body protein to a minimum, thus conserving the strength of the 

 patient. It will be seen that this procedure of bromatherapy is equally 

 indicated from the physiological, bacteriological, and biochemical view- 

 points. It is specifically in the interest of the host and equally directly 

 in opposition to the baneful activities of the parasite. It must be .realized 

 that bromatherapy, as outlined above, is subject to the same general 

 limitations as any other form of therapy. Damage already accomplished 



