130 MODE OF TRANSMISSION OF VELLOW FEVER 



monte, and Lazear, wlio were sent to Cuba to study 

 yellow fever. In Havana tliese observers found that 

 already Dr. C. J. Finlay had, as early as 1881, 

 enunciated the theory in no uncertain manner of the 

 propagation of yellow fever by the mosquito ; and, 

 influenced botli by this fact and, as they state, also 

 by the brilliant work of Ross and the Italian observers 

 in connection with the propagation of malaria by the 

 mosquito, as well as by certain observations of Carter, 

 they determined to experimentally investigate this 

 line of research. The results obtained by them were 

 most conclusive. 



The late Dr. Reed thus describes, in writing to 

 his wife, his feelings of joy at having solved with 

 his companions, Carroll, Agramonte, and Lazear, the 

 secret of the mode of transmission of yellow fever. 

 A volunteer having submitted liimself to be bitten 

 by some Stegomyia mosquitos, which had some days 

 previously bitten a patient suffering from undoubted 

 yellow fever, and having in consequence contracted 

 the disease. Reed proceeds : 



"It is with a great deal of pleasure that I hasten 

 to tell you tliat we have succeeded in producing a 

 case of unmistakable yellow fever by the bite of the 

 mosquito. 



" Our first case in the experimental camp developed 

 at 11.30 last night, commencing with a sudden chill 

 followed by fever. 



"The patient had been bitten at 11.30 on December 5, 

 and lience his attack followed just three and a half 

 days after the bite. As he had been in our camp 



